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TCR and CD28 Concomitant Stimulation Elicits a Distinctive Calcium Response in Naive T Cells

T cell activation is initiated upon ligand engagement of the T cell receptor (TCR) and costimulatory receptors. The CD28 molecule acts as a major costimulatory receptor in promoting full activation of naive T cells. However, despite extensive studies, why naive T cell activation requires concurrent...

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Detalles Bibliográficos
Autores principales:	Xia, Fan, Qian, Cheng-Rui, Xun, Zhou, Hamon, Yannick, Sartre, Anne-Marie, Formisano, Anthony, Mailfert, Sébastien, Phelipot, Marie-Claire, Billaudeau, Cyrille, Jaeger, Sébastien, Nunès, Jacques A., Guo, Xiao-Jun, He, Hai-Tao
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2018
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6288997/ https://www.ncbi.nlm.nih.gov/pubmed/30564247 http://dx.doi.org/10.3389/fimmu.2018.02864

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