Life-Threatening Primary Varicella Zoster Virus Infection With Hemophagocytic Lymphohistiocytosis-Like Disease in GATA2 Haploinsufficiency Accompanied by Expansion of Double Negative T-Lymphocytes

Two unrelated patients with GATA2-haploinsufficiency developed a hemophagocytic lymphohistiocytosis (HLH)-like disease during a varicella zoster virus (VZV) infection. High copy numbers of VZV were detected in the blood, and the patients were successfully treated with acyclovir and intravenous immun...

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Detalles Bibliográficos
Autores principales: Prader, Seraina, Felber, Matthias, Volkmer, Benjamin, Trück, Johannes, Schwieger-Briel, Agnes, Theiler, Martin, Weibel, Lisa, Hambleton, Sophie, Seipel, Katja, Vavassori, Stefano, Pachlopnik Schmid, Jana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6289061/
https://www.ncbi.nlm.nih.gov/pubmed/30564229
http://dx.doi.org/10.3389/fimmu.2018.02766

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