Transcriptome and protein interaction profiling in cancer cells with mutations in histone H3.3

Mutations of histone variant H3.3 are highly recurrent in childhood glioblastoma and in young adults with Giant Cell Tumor of the Bone (GCTB). The heterozygotic representation of the mutations in the tumors, and with potential histone H3 and H3.3 redundancy, suggest that the mutations are gain-of-fu...

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Detalles Bibliográficos
Autores principales: Lim, Jinyeong, Park, Joo Hyun, Baude, Annika, Fellenberg, Jörg, Zustin, Jozef, Haller, Florian, Krücken, Irene, Kang, Hyun Guy, Park, Yoon Jung, Plass, Christoph, Lindroth, Anders M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2018
Materias:
Data Descriptor
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6289111/
https://www.ncbi.nlm.nih.gov/pubmed/30532024
http://dx.doi.org/10.1038/sdata.2018.283

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