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Extensive Paneth cell metaplasia in an ovarian Krukenberg tumor: report of an unusual case and literature review

Paneth cells are classified as secretory cells which are normally found in the cecum and ascending colon. Their presence in other parts of the gastrointestinal tract is regarded as abnormal and indicates metaplasia. Paneth cells may also be rarely found in gastrointestinal, biliary and prostatic tum...

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Autores principales: Alrajban, Waleed Abdullah, Khubrani, Reham Ali, Almalki, Mamdouh Saad, Almassri, Ashraf, Alrikabi, Ammar Cherkess
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6289214/
https://www.ncbi.nlm.nih.gov/pubmed/30555671
http://dx.doi.org/10.1093/jscr/rjy323
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author Alrajban, Waleed Abdullah
Khubrani, Reham Ali
Almalki, Mamdouh Saad
Almassri, Ashraf
Alrikabi, Ammar Cherkess
author_facet Alrajban, Waleed Abdullah
Khubrani, Reham Ali
Almalki, Mamdouh Saad
Almassri, Ashraf
Alrikabi, Ammar Cherkess
author_sort Alrajban, Waleed Abdullah
collection PubMed
description Paneth cells are classified as secretory cells which are normally found in the cecum and ascending colon. Their presence in other parts of the gastrointestinal tract is regarded as abnormal and indicates metaplasia. Paneth cells may also be rarely found in gastrointestinal, biliary and prostatic tumors. The presence of Paneth cells in ovarian Krukenberg tumors is rare and to the best of our knowledge is restricted to metastatic appendiceal goblet cells tumors. We report a rare case of unilateral metastatic gastric carcinoma to the ovary in a 23-year-old female. This tumor showed unusual extensive Paneth cells metaplasia with classical signet ring cell morphology.
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spelling pubmed-62892142018-12-14 Extensive Paneth cell metaplasia in an ovarian Krukenberg tumor: report of an unusual case and literature review Alrajban, Waleed Abdullah Khubrani, Reham Ali Almalki, Mamdouh Saad Almassri, Ashraf Alrikabi, Ammar Cherkess J Surg Case Rep Case Report Paneth cells are classified as secretory cells which are normally found in the cecum and ascending colon. Their presence in other parts of the gastrointestinal tract is regarded as abnormal and indicates metaplasia. Paneth cells may also be rarely found in gastrointestinal, biliary and prostatic tumors. The presence of Paneth cells in ovarian Krukenberg tumors is rare and to the best of our knowledge is restricted to metastatic appendiceal goblet cells tumors. We report a rare case of unilateral metastatic gastric carcinoma to the ovary in a 23-year-old female. This tumor showed unusual extensive Paneth cells metaplasia with classical signet ring cell morphology. Oxford University Press 2018-12-11 /pmc/articles/PMC6289214/ /pubmed/30555671 http://dx.doi.org/10.1093/jscr/rjy323 Text en Published by Oxford University Press and JSCR Publishing Ltd. All rights reserved. © The Author(s) 2018. http://creativecommons.org/licenses/by-nc/4.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0/), which permits non-commercial re-use, distribution, and reproduction in any medium, provided the original work is properly cited. For commercial re-use, please contact journals.permissions@oup.com
spellingShingle Case Report
Alrajban, Waleed Abdullah
Khubrani, Reham Ali
Almalki, Mamdouh Saad
Almassri, Ashraf
Alrikabi, Ammar Cherkess
Extensive Paneth cell metaplasia in an ovarian Krukenberg tumor: report of an unusual case and literature review
title Extensive Paneth cell metaplasia in an ovarian Krukenberg tumor: report of an unusual case and literature review
title_full Extensive Paneth cell metaplasia in an ovarian Krukenberg tumor: report of an unusual case and literature review
title_fullStr Extensive Paneth cell metaplasia in an ovarian Krukenberg tumor: report of an unusual case and literature review
title_full_unstemmed Extensive Paneth cell metaplasia in an ovarian Krukenberg tumor: report of an unusual case and literature review
title_short Extensive Paneth cell metaplasia in an ovarian Krukenberg tumor: report of an unusual case and literature review
title_sort extensive paneth cell metaplasia in an ovarian krukenberg tumor: report of an unusual case and literature review
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6289214/
https://www.ncbi.nlm.nih.gov/pubmed/30555671
http://dx.doi.org/10.1093/jscr/rjy323
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