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MMP-9 inhibitors impair learning in spontaneously hypertensive rats
Vascular cognitive impairment dementia (VCID) is a major cause of cognitive loss in the elderly. Matrix metalloproteinases (MMPs) are a family of proteases involved in remodeling the extracellular matrix in development, injury and repair. Blood-brain barrier (BBB) disruption due to inflammation medi...
Autores principales: | Raz, Limor, Yang, Yi, Thompson, Jeffrey, Hobson, Sasha, Pesko, John, Mobashery, Shahriar, Chang, Mayland, Rosenberg, Gary |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6289411/ https://www.ncbi.nlm.nih.gov/pubmed/30533010 http://dx.doi.org/10.1371/journal.pone.0208357 |
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