A forward genetic screen reveals a primary role for Plasmodium falciparum Reticulocyte Binding Protein Homologue 2a and 2b in determining alternative erythrocyte invasion pathways

Invasion of human erythrocytes is essential for Plasmodium falciparum parasite survival and pathogenesis, and is also a complex phenotype. While some later steps in invasion appear to be invariant and essential, the earlier steps of recognition are controlled by a series of redundant, and only parti...

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Detalles Bibliográficos
Autores principales: Campino, Susana, Marin-Menendez, Alejandro, Kemp, Alison, Cross, Nadia, Drought, Laura, Otto, Thomas D., Benavente, Ernest Diez, Ravenhall, Matt, Schwach, Frank, Girling, Gareth, Manske, Magnus, Theron, Michel, Gould, Kelda, Drury, Eleanor, Clark, Taane G., Kwiatkowski, Dominic P., Pance, Alena, Rayner, Julian C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6289454/
https://www.ncbi.nlm.nih.gov/pubmed/30496294
http://dx.doi.org/10.1371/journal.ppat.1007436

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