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Mek1 coordinates meiotic progression with DNA break repair by directly phosphorylating and inhibiting the yeast pachytene exit regulator Ndt80
Meiotic recombination plays a critical role in sexual reproduction by creating crossovers between homologous chromosomes. These crossovers, along with sister chromatid cohesion, connect homologs to enable proper segregation at Meiosis I. Recombination is initiated by programmed double strand breaks...
Autores principales: | Chen, Xiangyu, Gaglione, Robert, Leong, Trevor, Bednor, Lauren, de los Santos, Teresa, Luk, Ed, Airola, Michael, Hollingsworth, Nancy M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6289461/ https://www.ncbi.nlm.nih.gov/pubmed/30496175 http://dx.doi.org/10.1371/journal.pgen.1007832 |
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