Rotavirus VP3 targets MAVS for degradation to inhibit type III interferon expression in intestinal epithelial cells

Rotaviruses (RVs), a leading cause of severe diarrhea in young children and many mammalian species, have evolved multiple strategies to counteract the host innate immunity, specifically interferon (IFN) signaling through RV non-structural protein 1 (NSP1). However, whether RV structural components a...

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Detalles Bibliográficos
Autores principales: Ding, Siyuan, Zhu, Shu, Ren, Lili, Feng, Ningguo, Song, Yanhua, Ge, Xiaomei, Li, Bin, Flavell, Richard A, Greenberg, Harry B
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2018
Materias:
Microbiology and Infectious Disease
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6289572/
https://www.ncbi.nlm.nih.gov/pubmed/30460894
http://dx.doi.org/10.7554/eLife.39494

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6289572/
https://www.ncbi.nlm.nih.gov/pubmed/30460894
http://dx.doi.org/10.7554/eLife.39494

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