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ARIADNA: machine learning method for ancient DNA variant discovery
Ancient DNA (aDNA) studies often rely on standard methods of mutation calling, optimized for high-quality contemporary DNA but not for excessive contamination, time- or environment-related damage of aDNA. In the absence of validated datasets and despite showing extreme sensitivity to aDNA quality, t...
Autores principales: | Kawash, Joseph K, Smith, Sean D, Karaiskos, Spyros, Grigoriev, Andrey |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6289774/ https://www.ncbi.nlm.nih.gov/pubmed/30215675 http://dx.doi.org/10.1093/dnares/dsy029 |
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