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Controlling Pd(IV) reductive-elimination pathways enables Pd(II)-catalyzed enantioselective C(sp(3))–H fluorination
The development of a Pd(II)-catalyzed enantioselective fluorination of C(sp(3))–H bonds would offer a new approach to making chiral organofluorines. However, such a strategy is particularly challenging because of the difficulty in differentiating prochiral C(sp(3))–H bonds through Pd(II)-insertion,...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6289870/ https://www.ncbi.nlm.nih.gov/pubmed/29892027 http://dx.doi.org/10.1038/s41557-018-0048-1 |