Single human B cell-derived monoclonal anti-Candida antibodies enhance phagocytosis and protect against disseminated candidiasis

The high global burden of over one million annual lethal fungal infections reflects a lack of protective vaccines, late diagnosis and inadequate chemotherapy. Here, we have generated a unique set of fully human anti-Candida monoclonal antibodies (mAbs) with diagnostic and therapeutic potential by ex...

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Detalles Bibliográficos
Autores principales: Rudkin, Fiona M., Raziunaite, Ingrida, Workman, Hillary, Essono, Sosthene, Belmonte, Rodrigo, MacCallum, Donna M., Johnson, Elizabeth M., Silva, Lisete M., Palma, Angelina S., Feizi, Ten, Jensen, Allan, Erwig, Lars P., Gow, Neil A. R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6290022/
https://www.ncbi.nlm.nih.gov/pubmed/30538246
http://dx.doi.org/10.1038/s41467-018-07738-1

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