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Interferon gamma (IFN-γ) negative CD4+ and CD8+ T-cells can produce immune mediators in response to viral antigens

Evaluation of antigen-specific T-cell responses to viral antigens is frequently performed on IFN-γ secreting cells. However, T-cells are capable of producing many more functions than just IFN-γ, some of which, like Perforin, are associated with immune protection in HIV-1 disease elite controllers. W...

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Detalles Bibliográficos
Autores principales:	Nakiboneka, Ritah, Mugaba, Susan, Auma, Betty O., Kintu, Christopher, Lindan, Christina, Nanteza, Mary Bridget, Kaleebu, Pontiano, Serwanga, Jennifer
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier Science 2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6290111/ https://www.ncbi.nlm.nih.gov/pubmed/30459072 http://dx.doi.org/10.1016/j.vaccine.2018.11.024

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