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Early interventional embolization in the treatment of cerebral aneurysm rupture

OBJECTIVE: To analyze the clinical effectiveness and safety of early interventional embolization in the treatment of ruptured cerebral aneurysm. METHODS: Eighty-eight patients with cerebral aneurysm rupture who were admitted to the hospital between February 2015 and October 2016 were selected as the...

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Autores principales: Jiang, Song, Xie, Xiufen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Professional Medical Publications 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6290242/
https://www.ncbi.nlm.nih.gov/pubmed/30559804
http://dx.doi.org/10.12669/pjms.346.15786
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author Jiang, Song
Xie, Xiufen
author_facet Jiang, Song
Xie, Xiufen
author_sort Jiang, Song
collection PubMed
description OBJECTIVE: To analyze the clinical effectiveness and safety of early interventional embolization in the treatment of ruptured cerebral aneurysm. METHODS: Eighty-eight patients with cerebral aneurysm rupture who were admitted to the hospital between February 2015 and October 2016 were selected as the research subjects and were randomly divided into a control group (N=44) and an observation group (N=44) using random number table. Patients in the control group were given interventional embolization three days after admission, while patients in the observation group were given interventional embolization within three days after admission. The complete, sub complete and incomplete embolization rates were compared between the two groups. The prognosis of the patients was evaluated using modified Rankin scale and modified Barthel index. The incidences of complications were recorded. RESULTS: The complete, sub-complete and incomplete embolization rates of the observation group and control group were significantly different (P<0.05). The modified Rankin score of the observation group was remarkably lower than that of the control group, and the modified Barthel index of the observation group was remarkably higher than that of the control group; the differences had statistical significance (P<0.05). The incidence of complications of the observation group was lower than that of the control group, and the difference had statistical significance (P<0.05). CONCLUSION: Early interventional embolization has satisfactory effect in the treatment of cerebral aneurysm rupture and effectively improve prognosis; hence it is worth promotion in clinical practice.
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spelling pubmed-62902422018-12-17 Early interventional embolization in the treatment of cerebral aneurysm rupture Jiang, Song Xie, Xiufen Pak J Med Sci Original Article OBJECTIVE: To analyze the clinical effectiveness and safety of early interventional embolization in the treatment of ruptured cerebral aneurysm. METHODS: Eighty-eight patients with cerebral aneurysm rupture who were admitted to the hospital between February 2015 and October 2016 were selected as the research subjects and were randomly divided into a control group (N=44) and an observation group (N=44) using random number table. Patients in the control group were given interventional embolization three days after admission, while patients in the observation group were given interventional embolization within three days after admission. The complete, sub complete and incomplete embolization rates were compared between the two groups. The prognosis of the patients was evaluated using modified Rankin scale and modified Barthel index. The incidences of complications were recorded. RESULTS: The complete, sub-complete and incomplete embolization rates of the observation group and control group were significantly different (P<0.05). The modified Rankin score of the observation group was remarkably lower than that of the control group, and the modified Barthel index of the observation group was remarkably higher than that of the control group; the differences had statistical significance (P<0.05). The incidence of complications of the observation group was lower than that of the control group, and the difference had statistical significance (P<0.05). CONCLUSION: Early interventional embolization has satisfactory effect in the treatment of cerebral aneurysm rupture and effectively improve prognosis; hence it is worth promotion in clinical practice. Professional Medical Publications 2018 /pmc/articles/PMC6290242/ /pubmed/30559804 http://dx.doi.org/10.12669/pjms.346.15786 Text en Copyright: © Pakistan Journal of Medical Sciences http://creativecommons.org/licenses/by/3.0 This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/3.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Original Article
Jiang, Song
Xie, Xiufen
Early interventional embolization in the treatment of cerebral aneurysm rupture
title Early interventional embolization in the treatment of cerebral aneurysm rupture
title_full Early interventional embolization in the treatment of cerebral aneurysm rupture
title_fullStr Early interventional embolization in the treatment of cerebral aneurysm rupture
title_full_unstemmed Early interventional embolization in the treatment of cerebral aneurysm rupture
title_short Early interventional embolization in the treatment of cerebral aneurysm rupture
title_sort early interventional embolization in the treatment of cerebral aneurysm rupture
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6290242/
https://www.ncbi.nlm.nih.gov/pubmed/30559804
http://dx.doi.org/10.12669/pjms.346.15786
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