Analysis of Whole-Genome Sequences for the Prediction of Penicillin Resistance and β-Lactamase Activity in Bacillus anthracis

Penicillin (PEN) is a low-cost option for anthrax treatment, but naturally occurring resistance has been reported. β-Lactamase expression (bla1, bla2) in Bacillus anthracis is regulated by a sigma factor (SigP) and its cognate anti-sigma factor (RsiP). Mutations leading to truncation of RsiP were pr...

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Detalles Bibliográficos
Autores principales: Gargis, A. S., McLaughlin, H. P., Conley, A. B., Lascols, C., Michel, P. A., Gee, J. E., Marston, C. K., Kolton, C. B., Rodriguez-R, L. M., Hoffmaster, A. R., Weigel, L. M., Sue, D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6290263/
https://www.ncbi.nlm.nih.gov/pubmed/30574557
http://dx.doi.org/10.1128/mSystems.00154-18

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