Sonic Hedgehog Signaling Pathway Mediates Proliferation and Migration of Fibroblast-Like Synoviocytes in Rheumatoid Arthritis via MAPK/ERK Signaling Pathway

Fibroblast-like synoviocytes (FLSs) are the major effector cells that lead to rheumatoid arthritis (RA) synovitis and joint destruction. Our previous studies showed that Sonic Hedgehog (SHH) signaling pathway is involved in aberrant activation of RA-FLSs and inhibition of SHH pathway decreases proli...

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Detalles Bibliográficos
Autores principales: Liu, Fang, Feng, Xiao Xue, Zhu, Shang Ling, Huang, Hong Yu, Chen, Ying Di, Pan, Yun Feng, June, Rayford R., Zheng, Song Guo, Huang, Jian Lin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6290332/
https://www.ncbi.nlm.nih.gov/pubmed/30568656
http://dx.doi.org/10.3389/fimmu.2018.02847

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6290332/
https://www.ncbi.nlm.nih.gov/pubmed/30568656
http://dx.doi.org/10.3389/fimmu.2018.02847

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