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Discovery of Antiamebic Compounds That Inhibit Cysteine Synthase From the Enteric Parasitic Protist Entamoeba histolytica by Screening of Microbial Secondary Metabolites

Amebiasis is caused by infection with the protozoan parasite Entamoeba histolytica. Although metronidazole has been a drug of choice against amebiasis for decades, it shows side effects and low efficacy against asymptomatic cyst carriers. In addition, metronidazole resistance has been documented for...

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Detalles Bibliográficos
Autores principales:	Mori, Mihoko, Tsuge, Satoshi, Fukasawa, Wataru, Jeelani, Ghulam, Nakada-Tsukui, Kumiko, Nonaka, Kenichi, Matsumoto, Atsuko, Ōmura, Satoshi, Nozaki, Tomoyoshi, Shiomi, Kazuro
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2018
Materias:	Cellular and Infection Microbiology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6290340/ https://www.ncbi.nlm.nih.gov/pubmed/30568921 http://dx.doi.org/10.3389/fcimb.2018.00409

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