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Polarization of Human Macrophages by Interleukin-4 Does Not Require ATP-Citrate Lyase

Macrophages exposed to the Th2 cytokines interleukin (IL) IL-4 and IL-13 exhibit a distinct transcriptional response, commonly referred to as M2 polarization. Recently, IL-4-induced polarization of murine bone marrow-derived macrophages (BMDMs) has been linked to acetyl-CoA levels through the activi...

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Detalles Bibliográficos
Autores principales:	Namgaladze, Dmitry, Zukunft, Sven, Schnütgen, Frank, Kurrle, Nina, Fleming, Ingrid, Fuhrmann, Dominik, Brüne, Bernhard
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2018
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6290342/ https://www.ncbi.nlm.nih.gov/pubmed/30568658 http://dx.doi.org/10.3389/fimmu.2018.02858

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