Blockade of the Adenosine 2A Receptor Mitigates the Cardiomyopathy Induced by Loss of Plakophilin-2 Expression

Background: Mutations in plakophilin-2 (PKP2) are the most common cause of familial Arrhythmogenic Right Ventricular Cardiomyopathy, a disease characterized by ventricular arrhythmias, sudden death, and progressive fibrofatty cardiomyopathy. The relation between loss of PKP2 expression and structura...

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Detalles Bibliográficos
Autores principales: Cerrone, Marina, van Opbergen, Chantal J. M., Malkani, Kabir, Irrera, Natasha, Zhang, Mingliang, Van Veen, Toon A. B., Cronstein, Bruce, Delmar, Mario
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Physiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6290386/
https://www.ncbi.nlm.nih.gov/pubmed/30568602
http://dx.doi.org/10.3389/fphys.2018.01750

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6290386/
https://www.ncbi.nlm.nih.gov/pubmed/30568602
http://dx.doi.org/10.3389/fphys.2018.01750

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