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Seborrheic Keratoses – The Most Common Benign Skin Tumor of Humans. Clinical presentation and an update on pathogenesis and treatment options

Seborrheic keratoses (SK) are the most common skin tumour of humanity. The incidence of this purely benign epithelial proliferation is increasing with age and exposure to ultraviolet light. It has a remarkable variability in its clinical presentation raising some differential diagnoses. Recently, on...

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Autor principal: Wollina, Uwe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Republic of Macedonia 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6290447/
https://www.ncbi.nlm.nih.gov/pubmed/30559899
http://dx.doi.org/10.3889/oamjms.2018.460
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author Wollina, Uwe
author_facet Wollina, Uwe
author_sort Wollina, Uwe
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description Seborrheic keratoses (SK) are the most common skin tumour of humanity. The incidence of this purely benign epithelial proliferation is increasing with age and exposure to ultraviolet light. It has a remarkable variability in its clinical presentation raising some differential diagnoses. Recently, oncogenic mutations have been detected involved in the development of SK, which, however, do not bear the risk of malignant transformation. SK may also develop with the use of modern targeted drugs for the treatment of malignancies. The classical treatment options for SK are cryotherapy and curettage. Recently, topical treatment with 40% hydrogen peroxide and the nitric-zinc complex has been investigated. Ablative laser therapy is an effective treatment as well.
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spelling pubmed-62904472018-12-17 Seborrheic Keratoses – The Most Common Benign Skin Tumor of Humans. Clinical presentation and an update on pathogenesis and treatment options Wollina, Uwe Open Access Maced J Med Sci Review Article Seborrheic keratoses (SK) are the most common skin tumour of humanity. The incidence of this purely benign epithelial proliferation is increasing with age and exposure to ultraviolet light. It has a remarkable variability in its clinical presentation raising some differential diagnoses. Recently, oncogenic mutations have been detected involved in the development of SK, which, however, do not bear the risk of malignant transformation. SK may also develop with the use of modern targeted drugs for the treatment of malignancies. The classical treatment options for SK are cryotherapy and curettage. Recently, topical treatment with 40% hydrogen peroxide and the nitric-zinc complex has been investigated. Ablative laser therapy is an effective treatment as well. Republic of Macedonia 2018-11-23 /pmc/articles/PMC6290447/ /pubmed/30559899 http://dx.doi.org/10.3889/oamjms.2018.460 Text en Copyright: © 2018 Uwe Wollina. http://creativecommons.org/licenses/CC BY-NC/4.0 This is an open-access article distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 International License (CC BY-NC 4.0).
spellingShingle Review Article
Wollina, Uwe
Seborrheic Keratoses – The Most Common Benign Skin Tumor of Humans. Clinical presentation and an update on pathogenesis and treatment options
title Seborrheic Keratoses – The Most Common Benign Skin Tumor of Humans. Clinical presentation and an update on pathogenesis and treatment options
title_full Seborrheic Keratoses – The Most Common Benign Skin Tumor of Humans. Clinical presentation and an update on pathogenesis and treatment options
title_fullStr Seborrheic Keratoses – The Most Common Benign Skin Tumor of Humans. Clinical presentation and an update on pathogenesis and treatment options
title_full_unstemmed Seborrheic Keratoses – The Most Common Benign Skin Tumor of Humans. Clinical presentation and an update on pathogenesis and treatment options
title_short Seborrheic Keratoses – The Most Common Benign Skin Tumor of Humans. Clinical presentation and an update on pathogenesis and treatment options
title_sort seborrheic keratoses – the most common benign skin tumor of humans. clinical presentation and an update on pathogenesis and treatment options
topic Review Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6290447/
https://www.ncbi.nlm.nih.gov/pubmed/30559899
http://dx.doi.org/10.3889/oamjms.2018.460
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