Cargando…

Improving palliative care with deep learning

BACKGROUND: Access to palliative care is a key quality metric which most healthcare organizations strive to improve. The primary challenges to increasing palliative care access are a combination of physicians over-estimating patient prognoses, and a shortage of palliative staff in general. This, in...

Descripción completa

Detalles Bibliográficos
Autores principales: Avati, Anand, Jung, Kenneth, Harman, Stephanie, Downing, Lance, Ng, Andrew, Shah, Nigam H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6290509/
https://www.ncbi.nlm.nih.gov/pubmed/30537977
http://dx.doi.org/10.1186/s12911-018-0677-8
_version_ 1783380100279959552
author Avati, Anand
Jung, Kenneth
Harman, Stephanie
Downing, Lance
Ng, Andrew
Shah, Nigam H.
author_facet Avati, Anand
Jung, Kenneth
Harman, Stephanie
Downing, Lance
Ng, Andrew
Shah, Nigam H.
author_sort Avati, Anand
collection PubMed
description BACKGROUND: Access to palliative care is a key quality metric which most healthcare organizations strive to improve. The primary challenges to increasing palliative care access are a combination of physicians over-estimating patient prognoses, and a shortage of palliative staff in general. This, in combination with treatment inertia can result in a mismatch between patient wishes, and their actual care towards the end of life. METHODS: In this work, we address this problem, with Institutional Review Board approval, using machine learning and Electronic Health Record (EHR) data of patients. We train a Deep Neural Network model on the EHR data of patients from previous years, to predict mortality of patients within the next 3-12 month period. This prediction is used as a proxy decision for identifying patients who could benefit from palliative care. RESULTS: The EHR data of all admitted patients are evaluated every night by this algorithm, and the palliative care team is automatically notified of the list of patients with a positive prediction. In addition, we present a novel technique for decision interpretation, using which we provide explanations for the model’s predictions. CONCLUSION: The automatic screening and notification saves the palliative care team the burden of time consuming chart reviews of all patients, and allows them to take a proactive approach in reaching out to such patients rather then relying on referrals from the treating physicians.
format Online
Article
Text
id pubmed-6290509
institution National Center for Biotechnology Information
language English
publishDate 2018
publisher BioMed Central
record_format MEDLINE/PubMed
spelling pubmed-62905092018-12-17 Improving palliative care with deep learning Avati, Anand Jung, Kenneth Harman, Stephanie Downing, Lance Ng, Andrew Shah, Nigam H. BMC Med Inform Decis Mak Research BACKGROUND: Access to palliative care is a key quality metric which most healthcare organizations strive to improve. The primary challenges to increasing palliative care access are a combination of physicians over-estimating patient prognoses, and a shortage of palliative staff in general. This, in combination with treatment inertia can result in a mismatch between patient wishes, and their actual care towards the end of life. METHODS: In this work, we address this problem, with Institutional Review Board approval, using machine learning and Electronic Health Record (EHR) data of patients. We train a Deep Neural Network model on the EHR data of patients from previous years, to predict mortality of patients within the next 3-12 month period. This prediction is used as a proxy decision for identifying patients who could benefit from palliative care. RESULTS: The EHR data of all admitted patients are evaluated every night by this algorithm, and the palliative care team is automatically notified of the list of patients with a positive prediction. In addition, we present a novel technique for decision interpretation, using which we provide explanations for the model’s predictions. CONCLUSION: The automatic screening and notification saves the palliative care team the burden of time consuming chart reviews of all patients, and allows them to take a proactive approach in reaching out to such patients rather then relying on referrals from the treating physicians. BioMed Central 2018-12-12 /pmc/articles/PMC6290509/ /pubmed/30537977 http://dx.doi.org/10.1186/s12911-018-0677-8 Text en © The Author(s) 2018 Open Access This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver(http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.
spellingShingle Research
Avati, Anand
Jung, Kenneth
Harman, Stephanie
Downing, Lance
Ng, Andrew
Shah, Nigam H.
Improving palliative care with deep learning
title Improving palliative care with deep learning
title_full Improving palliative care with deep learning
title_fullStr Improving palliative care with deep learning
title_full_unstemmed Improving palliative care with deep learning
title_short Improving palliative care with deep learning
title_sort improving palliative care with deep learning
topic Research
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6290509/
https://www.ncbi.nlm.nih.gov/pubmed/30537977
http://dx.doi.org/10.1186/s12911-018-0677-8
work_keys_str_mv AT avatianand improvingpalliativecarewithdeeplearning
AT jungkenneth improvingpalliativecarewithdeeplearning
AT harmanstephanie improvingpalliativecarewithdeeplearning
AT downinglance improvingpalliativecarewithdeeplearning
AT ngandrew improvingpalliativecarewithdeeplearning
AT shahnigamh improvingpalliativecarewithdeeplearning