Bidirectional gut-brain-microbiota axis as a potential link between inflammatory bowel disease and ischemic stroke

Emerging evidence suggests that gut-brain-microbiota axis (GBMAx) may play a pivotal role linking gastrointestinal and neuronal disease. In this review, we summarize the latest advances in studies of GBMAx in inflammatory bowel disease (IBD) and ischemic stroke. A more thorough understanding of the...

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Autores principales: Zhao, Liang, Xiong, Qiutang, Stary, Creed M., Mahgoub, Omer Kamal, Ye, Yingze, Gu, Lijuan, Xiong, Xiaoxing, Zhu, Shengmei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6290529/
https://www.ncbi.nlm.nih.gov/pubmed/30537997
http://dx.doi.org/10.1186/s12974-018-1382-3
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author Zhao, Liang
Xiong, Qiutang
Stary, Creed M.
Mahgoub, Omer Kamal
Ye, Yingze
Gu, Lijuan
Xiong, Xiaoxing
Zhu, Shengmei
author_facet Zhao, Liang
Xiong, Qiutang
Stary, Creed M.
Mahgoub, Omer Kamal
Ye, Yingze
Gu, Lijuan
Xiong, Xiaoxing
Zhu, Shengmei
author_sort Zhao, Liang
collection PubMed
description Emerging evidence suggests that gut-brain-microbiota axis (GBMAx) may play a pivotal role linking gastrointestinal and neuronal disease. In this review, we summarize the latest advances in studies of GBMAx in inflammatory bowel disease (IBD) and ischemic stroke. A more thorough understanding of the GBMAx could advance our knowledge about the pathophysiology of IBD and ischemic stroke and help to identify novel therapeutic targets via modulation of the GBMAx.
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spelling pubmed-62905292018-12-17 Bidirectional gut-brain-microbiota axis as a potential link between inflammatory bowel disease and ischemic stroke Zhao, Liang Xiong, Qiutang Stary, Creed M. Mahgoub, Omer Kamal Ye, Yingze Gu, Lijuan Xiong, Xiaoxing Zhu, Shengmei J Neuroinflammation Review Emerging evidence suggests that gut-brain-microbiota axis (GBMAx) may play a pivotal role linking gastrointestinal and neuronal disease. In this review, we summarize the latest advances in studies of GBMAx in inflammatory bowel disease (IBD) and ischemic stroke. A more thorough understanding of the GBMAx could advance our knowledge about the pathophysiology of IBD and ischemic stroke and help to identify novel therapeutic targets via modulation of the GBMAx. BioMed Central 2018-12-11 /pmc/articles/PMC6290529/ /pubmed/30537997 http://dx.doi.org/10.1186/s12974-018-1382-3 Text en © The Author(s). 2018 Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.
spellingShingle Review
Zhao, Liang
Xiong, Qiutang
Stary, Creed M.
Mahgoub, Omer Kamal
Ye, Yingze
Gu, Lijuan
Xiong, Xiaoxing
Zhu, Shengmei
Bidirectional gut-brain-microbiota axis as a potential link between inflammatory bowel disease and ischemic stroke
title Bidirectional gut-brain-microbiota axis as a potential link between inflammatory bowel disease and ischemic stroke
title_full Bidirectional gut-brain-microbiota axis as a potential link between inflammatory bowel disease and ischemic stroke
title_fullStr Bidirectional gut-brain-microbiota axis as a potential link between inflammatory bowel disease and ischemic stroke
title_full_unstemmed Bidirectional gut-brain-microbiota axis as a potential link between inflammatory bowel disease and ischemic stroke
title_short Bidirectional gut-brain-microbiota axis as a potential link between inflammatory bowel disease and ischemic stroke
title_sort bidirectional gut-brain-microbiota axis as a potential link between inflammatory bowel disease and ischemic stroke
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6290529/
https://www.ncbi.nlm.nih.gov/pubmed/30537997
http://dx.doi.org/10.1186/s12974-018-1382-3
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