Bacterial outer membrane vesicles, a potential vaccine candidate in interactions with host cells based

Both Gram-Positive and Gram-Negative bacteria can secrete outer membrane vesicles (OMVs) in their growth and metabolism process. Originally, OMVs were considered as a by-product of bacterial merisis. However, many scientists have reported the important role of OMVs in many fields recently. In this r...

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Detalles Bibliográficos
Autores principales: Cai, Wei, Kesavan, Dinesh Kumar, Wan, Jie, Abdelaziz, Mohamed Hamed, Su, Zhaoliang, Xu, Huaxi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6290530/
https://www.ncbi.nlm.nih.gov/pubmed/30537996
http://dx.doi.org/10.1186/s13000-018-0768-y
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author Cai, Wei
Kesavan, Dinesh Kumar
Wan, Jie
Abdelaziz, Mohamed Hamed
Su, Zhaoliang
Xu, Huaxi
author_facet Cai, Wei
Kesavan, Dinesh Kumar
Wan, Jie
Abdelaziz, Mohamed Hamed
Su, Zhaoliang
Xu, Huaxi
author_sort Cai, Wei
collection PubMed
description Both Gram-Positive and Gram-Negative bacteria can secrete outer membrane vesicles (OMVs) in their growth and metabolism process. Originally, OMVs were considered as a by-product of bacterial merisis. However, many scientists have reported the important role of OMVs in many fields recently. In this review, we briefly introduce OMVs biological functions and then summarize the findings about the OMVs interactions with host cells. At last, we will make an expectation about the prospects of the application of OMVs as vaccines.
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spelling pubmed-62905302018-12-17 Bacterial outer membrane vesicles, a potential vaccine candidate in interactions with host cells based Cai, Wei Kesavan, Dinesh Kumar Wan, Jie Abdelaziz, Mohamed Hamed Su, Zhaoliang Xu, Huaxi Diagn Pathol Review Both Gram-Positive and Gram-Negative bacteria can secrete outer membrane vesicles (OMVs) in their growth and metabolism process. Originally, OMVs were considered as a by-product of bacterial merisis. However, many scientists have reported the important role of OMVs in many fields recently. In this review, we briefly introduce OMVs biological functions and then summarize the findings about the OMVs interactions with host cells. At last, we will make an expectation about the prospects of the application of OMVs as vaccines. BioMed Central 2018-12-11 /pmc/articles/PMC6290530/ /pubmed/30537996 http://dx.doi.org/10.1186/s13000-018-0768-y Text en © The Author(s). 2018 Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.
spellingShingle Review
Cai, Wei
Kesavan, Dinesh Kumar
Wan, Jie
Abdelaziz, Mohamed Hamed
Su, Zhaoliang
Xu, Huaxi
Bacterial outer membrane vesicles, a potential vaccine candidate in interactions with host cells based
title Bacterial outer membrane vesicles, a potential vaccine candidate in interactions with host cells based
title_full Bacterial outer membrane vesicles, a potential vaccine candidate in interactions with host cells based
title_fullStr Bacterial outer membrane vesicles, a potential vaccine candidate in interactions with host cells based
title_full_unstemmed Bacterial outer membrane vesicles, a potential vaccine candidate in interactions with host cells based
title_short Bacterial outer membrane vesicles, a potential vaccine candidate in interactions with host cells based
title_sort bacterial outer membrane vesicles, a potential vaccine candidate in interactions with host cells based
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6290530/
https://www.ncbi.nlm.nih.gov/pubmed/30537996
http://dx.doi.org/10.1186/s13000-018-0768-y
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