A New Triterpenoid Saponin from Abrus precatorius Linn

A new triterpenoid saponin, 3-O-β-D-glucopyranosyl-(1→2)-β-D-glucopyranosyl subprogenin D (1), together with six known triterpenoids: subprogenin D (2), abrusgenic acid (3), triptotriterpenic acid B (4), abruslactone A (5), abrusogenin (6) and abrusoside C (7) were isolated from the leaves and stems...

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Autores principales: Xiao, Zhi-Hui, Wang, Fa-Zuo, Sun, Ai-Jun, Li, Chuan-Rong, Huang, Cai-Guo, Zhang, Si
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2011
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6290555/
https://www.ncbi.nlm.nih.gov/pubmed/22210168
http://dx.doi.org/10.3390/molecules17010295
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author Xiao, Zhi-Hui
Wang, Fa-Zuo
Sun, Ai-Jun
Li, Chuan-Rong
Huang, Cai-Guo
Zhang, Si
author_facet Xiao, Zhi-Hui
Wang, Fa-Zuo
Sun, Ai-Jun
Li, Chuan-Rong
Huang, Cai-Guo
Zhang, Si
author_sort Xiao, Zhi-Hui
collection PubMed
description A new triterpenoid saponin, 3-O-β-D-glucopyranosyl-(1→2)-β-D-glucopyranosyl subprogenin D (1), together with six known triterpenoids: subprogenin D (2), abrusgenic acid (3), triptotriterpenic acid B (4), abruslactone A (5), abrusogenin (6) and abrusoside C (7) were isolated from the leaves and stems of Abrus precatorius. Their structures were elucidated on the basis of physical and NMR analysis, respectively. Compounds 5 and 6 showed moderate cytotoxicity against MCF-7, SW1990, Hela, and Du-145 cell lines. Compounds 1, 2 and 4 were isolated from this plant for the first time.
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spelling pubmed-62905552018-12-12 A New Triterpenoid Saponin from Abrus precatorius Linn Xiao, Zhi-Hui Wang, Fa-Zuo Sun, Ai-Jun Li, Chuan-Rong Huang, Cai-Guo Zhang, Si Molecules Article A new triterpenoid saponin, 3-O-β-D-glucopyranosyl-(1→2)-β-D-glucopyranosyl subprogenin D (1), together with six known triterpenoids: subprogenin D (2), abrusgenic acid (3), triptotriterpenic acid B (4), abruslactone A (5), abrusogenin (6) and abrusoside C (7) were isolated from the leaves and stems of Abrus precatorius. Their structures were elucidated on the basis of physical and NMR analysis, respectively. Compounds 5 and 6 showed moderate cytotoxicity against MCF-7, SW1990, Hela, and Du-145 cell lines. Compounds 1, 2 and 4 were isolated from this plant for the first time. MDPI 2011-12-30 /pmc/articles/PMC6290555/ /pubmed/22210168 http://dx.doi.org/10.3390/molecules17010295 Text en © 2011 by the authors; http://creativecommons.org/licenses/by/3.0/ licensee MDPI, Basel, Switzerland. This article is an open-access article distributed under the terms and conditions of the Creative Commons Attribution license (http://creativecommons.org/licenses/by/3.0/).
spellingShingle Article
Xiao, Zhi-Hui
Wang, Fa-Zuo
Sun, Ai-Jun
Li, Chuan-Rong
Huang, Cai-Guo
Zhang, Si
A New Triterpenoid Saponin from Abrus precatorius Linn
title A New Triterpenoid Saponin from Abrus precatorius Linn
title_full A New Triterpenoid Saponin from Abrus precatorius Linn
title_fullStr A New Triterpenoid Saponin from Abrus precatorius Linn
title_full_unstemmed A New Triterpenoid Saponin from Abrus precatorius Linn
title_short A New Triterpenoid Saponin from Abrus precatorius Linn
title_sort new triterpenoid saponin from abrus precatorius linn
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6290555/
https://www.ncbi.nlm.nih.gov/pubmed/22210168
http://dx.doi.org/10.3390/molecules17010295
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