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microRNA-29b mediates fibrotic induction of human xylosyltransferase-I in human dermal fibroblasts via the Sp1 pathway

Diminished microRNA-29b levels have recently been revealed to provoke increased expression and accumulation of extracellular matrix molecules, such as collagens in fibrotic remodeling. Subsequently, the aim of this study was to find out whether microRNA-29b might also regulate human xylosyltransfera...

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Detalles Bibliográficos
Autores principales: Riedel, Lara, Fischer, Bastian, Ly, Thanh-Diep, Hendig, Doris, Kuhn, Joachim, Knabbe, Cornelius, Faust, Isabel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6290791/
https://www.ncbi.nlm.nih.gov/pubmed/30542210
http://dx.doi.org/10.1038/s41598-018-36217-2