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Regeneration – A New Therapeutic Dimension in Otorhinolaryngology
Regeneration as a therapeutic priniciple and regenerative medicine in general are promising new strategies to add new therapeutic dimensions to our current treatment options. Today, reconstructive surgery, drugs and implants such as the cochlear implant can replace the functions of damaged tissues....
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
© Georg Thieme Verlag KG
2018
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6290928/ https://www.ncbi.nlm.nih.gov/pubmed/29905357 http://dx.doi.org/10.1055/s-0043-122309 |
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author | Rotter, Nicole Zenobi-Wong, Marcy |
author_facet | Rotter, Nicole Zenobi-Wong, Marcy |
author_sort | Rotter, Nicole |
collection | PubMed |
description | Regeneration as a therapeutic priniciple and regenerative medicine in general are promising new strategies to add new therapeutic dimensions to our current treatment options. Today, reconstructive surgery, drugs and implants such as the cochlear implant can replace the functions of damaged tissues. In contrast, regenerative therapies aim at the replacement of the damaged tissues themselves while at the same time replacing their lost tissue function. In this review article new technologies such as 3D-bioprinting and the application of decellularised tissues as biomaterials are introduced and explained. A summary of current preclinical and clinical regenerative studies in otorhinolaryngology is complementing these basic aspects. |
format | Online Article Text |
id | pubmed-6290928 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2018 |
publisher | © Georg Thieme Verlag KG |
record_format | MEDLINE/PubMed |
spelling | pubmed-62909282018-12-13 Regeneration – A New Therapeutic Dimension in Otorhinolaryngology Rotter, Nicole Zenobi-Wong, Marcy Laryngorhinootologie Regeneration as a therapeutic priniciple and regenerative medicine in general are promising new strategies to add new therapeutic dimensions to our current treatment options. Today, reconstructive surgery, drugs and implants such as the cochlear implant can replace the functions of damaged tissues. In contrast, regenerative therapies aim at the replacement of the damaged tissues themselves while at the same time replacing their lost tissue function. In this review article new technologies such as 3D-bioprinting and the application of decellularised tissues as biomaterials are introduced and explained. A summary of current preclinical and clinical regenerative studies in otorhinolaryngology is complementing these basic aspects. © Georg Thieme Verlag KG 2018-03 2018-03-22 /pmc/articles/PMC6290928/ /pubmed/29905357 http://dx.doi.org/10.1055/s-0043-122309 Text en https://creativecommons.org/licenses/by-nc-nd/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivatives License, which permits unrestricted reproduction and distribution, for non-commercial purposes only; and use and reproduction, but not distribution, of adapted material for non-commercial purposes only, provided the original work is properly cited. |
spellingShingle | Rotter, Nicole Zenobi-Wong, Marcy Regeneration – A New Therapeutic Dimension in Otorhinolaryngology |
title | Regeneration – A New Therapeutic Dimension in Otorhinolaryngology |
title_full | Regeneration – A New Therapeutic Dimension in Otorhinolaryngology |
title_fullStr | Regeneration – A New Therapeutic Dimension in Otorhinolaryngology |
title_full_unstemmed | Regeneration – A New Therapeutic Dimension in Otorhinolaryngology |
title_short | Regeneration – A New Therapeutic Dimension in Otorhinolaryngology |
title_sort | regeneration – a new therapeutic dimension in otorhinolaryngology |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6290928/ https://www.ncbi.nlm.nih.gov/pubmed/29905357 http://dx.doi.org/10.1055/s-0043-122309 |
work_keys_str_mv | AT rotternicole regenerationanewtherapeuticdimensioninotorhinolaryngology AT zenobiwongmarcy regenerationanewtherapeuticdimensioninotorhinolaryngology |