Cargando…

Regeneration – A New Therapeutic Dimension in Otorhinolaryngology

Regeneration as a therapeutic priniciple and regenerative medicine in general are promising new strategies to add new therapeutic dimensions to our current treatment options. Today, reconstructive surgery, drugs and implants such as the cochlear implant can replace the functions of damaged tissues....

Descripción completa

Detalles Bibliográficos
Autores principales: Rotter, Nicole, Zenobi-Wong, Marcy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: © Georg Thieme Verlag KG 2018
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6290928/
https://www.ncbi.nlm.nih.gov/pubmed/29905357
http://dx.doi.org/10.1055/s-0043-122309
_version_ 1783380176453763072
author Rotter, Nicole
Zenobi-Wong, Marcy
author_facet Rotter, Nicole
Zenobi-Wong, Marcy
author_sort Rotter, Nicole
collection PubMed
description Regeneration as a therapeutic priniciple and regenerative medicine in general are promising new strategies to add new therapeutic dimensions to our current treatment options. Today, reconstructive surgery, drugs and implants such as the cochlear implant can replace the functions of damaged tissues. In contrast, regenerative therapies aim at the replacement of the damaged tissues themselves while at the same time replacing their lost tissue function. In this review article new technologies such as 3D-bioprinting and the application of decellularised tissues as biomaterials are introduced and explained. A summary of current preclinical and clinical regenerative studies in otorhinolaryngology is complementing these basic aspects.
format Online
Article
Text
id pubmed-6290928
institution National Center for Biotechnology Information
language English
publishDate 2018
publisher © Georg Thieme Verlag KG
record_format MEDLINE/PubMed
spelling pubmed-62909282018-12-13 Regeneration – A New Therapeutic Dimension in Otorhinolaryngology Rotter, Nicole Zenobi-Wong, Marcy Laryngorhinootologie Regeneration as a therapeutic priniciple and regenerative medicine in general are promising new strategies to add new therapeutic dimensions to our current treatment options. Today, reconstructive surgery, drugs and implants such as the cochlear implant can replace the functions of damaged tissues. In contrast, regenerative therapies aim at the replacement of the damaged tissues themselves while at the same time replacing their lost tissue function. In this review article new technologies such as 3D-bioprinting and the application of decellularised tissues as biomaterials are introduced and explained. A summary of current preclinical and clinical regenerative studies in otorhinolaryngology is complementing these basic aspects. © Georg Thieme Verlag KG 2018-03 2018-03-22 /pmc/articles/PMC6290928/ /pubmed/29905357 http://dx.doi.org/10.1055/s-0043-122309 Text en https://creativecommons.org/licenses/by-nc-nd/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivatives License, which permits unrestricted reproduction and distribution, for non-commercial purposes only; and use and reproduction, but not distribution, of adapted material for non-commercial purposes only, provided the original work is properly cited.
spellingShingle Rotter, Nicole
Zenobi-Wong, Marcy
Regeneration – A New Therapeutic Dimension in Otorhinolaryngology
title Regeneration – A New Therapeutic Dimension in Otorhinolaryngology
title_full Regeneration – A New Therapeutic Dimension in Otorhinolaryngology
title_fullStr Regeneration – A New Therapeutic Dimension in Otorhinolaryngology
title_full_unstemmed Regeneration – A New Therapeutic Dimension in Otorhinolaryngology
title_short Regeneration – A New Therapeutic Dimension in Otorhinolaryngology
title_sort regeneration – a new therapeutic dimension in otorhinolaryngology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6290928/
https://www.ncbi.nlm.nih.gov/pubmed/29905357
http://dx.doi.org/10.1055/s-0043-122309
work_keys_str_mv AT rotternicole regenerationanewtherapeuticdimensioninotorhinolaryngology
AT zenobiwongmarcy regenerationanewtherapeuticdimensioninotorhinolaryngology