Clinical impact of measurable residual disease monitoring by ultradeep next generation sequencing in NPM1 mutated acute myeloid leukemia

Detection of measurable residual disease (MRD) by mutation specific techniques has prognostic relevance in NPM1 mutated AML (NPM1(mut) AML). However, the clinical utility of next generation sequencing (NGS) to detect MRD in AML remains unproven. We analysed the clinical significance of monitoring MR...

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Detalles Bibliográficos
Autores principales: Patkar, Nikhil, Kodgule, Rohan, Kakirde, Chinmayee, Raval, Goutham, Bhanshe, Prasanna, Joshi, Swapnali, Chaudhary, Shruti, Badrinath, Y., Ghoghale, Sitaram, Kadechkar, Shraddha, Khizer, Syed Hasan, Kannan, Sadhana, Shetty, Dhanalaxmi, Gokarn, Anant, Punatkar, Sachin, Jain, Hasmukh, Bagal, Bhausaheb, Menon, Hari, Sengar, Manju, Khattry, Navin, Tembhare, Prashant, Subramanian, Papagudi, Gujral, Sumeet
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2018
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6290958/
https://www.ncbi.nlm.nih.gov/pubmed/30564301
http://dx.doi.org/10.18632/oncotarget.26400

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