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The Effect of Gluten Free Diet on Components of Metabolic Syndrome: A Randomized Clinical Trial

BACKGROUND: This study aimed to assess the effects of Gluten free diet (GFD) on components of metabolic syndrome (MES). MATERIALS AND METHODS: In this randomized clinical trial, 50 subjects diagnosed with MES were randomly divided into two groups (n=25). The first group received a GFD and the second...

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Detalles Bibliográficos
Autores principales: Ehteshami, Mehdi, Shakerhosseini, Rahebeh, Sedaghat, Fatemeh, Hedayati, Mehdi, Eini-Zinab, Hassan, Hekmatdoost, Azita
Formato: Online Artículo Texto
Lenguaje:English
Publicado: West Asia Organization for Cancer Prevention 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6291063/
https://www.ncbi.nlm.nih.gov/pubmed/30362336
http://dx.doi.org/10.22034/APJCP.2018.19.10.2979
Descripción
Sumario:BACKGROUND: This study aimed to assess the effects of Gluten free diet (GFD) on components of metabolic syndrome (MES). MATERIALS AND METHODS: In this randomized clinical trial, 50 subjects diagnosed with MES were randomly divided into two groups (n=25). The first group received a GFD and the second group continued their regular diet. Biochemical markers of MES and blood pressure were measured before and after 8-week intervention. RESULTS: Forty five subjects completed the study. A post-hoc comparison of the groups showed no effects of the GFD and control diet on LDL cholesterol, total cholesterol, fasting insulin, HOMA-IR, systolic and diastolic blood pressure levels. The GFD reduced fasting blood glucose, waist circumference (WC) and serum triglyceride concentration significantly compared with the control diet (p<0.05). CONCLUSION: Short-term GFD reduced WC and improved glycemic control and Triglyceride level in subjects with the metabolic syndrome.