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Improved multilineage human hematopoietic reconstitution and function in NSGS mice

Genetic manipulation of NOD/SCID (NS) mice has yielded numerous sub-strains with specific traits useful for the study of human hematopoietic xenografts, each with unique characteristics. Here, we have compared the engraftment and output of umbilical cord blood (UCB) CD34+ cells in four immune-defici...

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Detalles Bibliográficos
Autores principales: Wunderlich, Mark, Chou, Fu-Sheng, Sexton, Christina, Presicce, Pietro, Chougnet, Claire A., Aliberti, Julio, Mulloy, James C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6291127/
https://www.ncbi.nlm.nih.gov/pubmed/30540841
http://dx.doi.org/10.1371/journal.pone.0209034