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Neutralization of Clostridium difficile toxin B with V(H)H-Fc fusions targeting the delivery and CROPs domains

An increasing number of antibody-based therapies are being considered for controlling bacterial infections, including Clostridium difficile by targeting toxins A and B. In an effort to develop novel C. difficile immunotherapeutics, we previously isolated several single-domain antibodies (V(H)Hs) cap...

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Detalles Bibliográficos
Autores principales:	Hussack, Greg, Ryan, Shannon, van Faassen, Henk, Rossotti, Martin, MacKenzie, C. Roger, Tanha, Jamshid
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2018
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6291252/ https://www.ncbi.nlm.nih.gov/pubmed/30540857 http://dx.doi.org/10.1371/journal.pone.0208978

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