No Impact of Probiotics to Reduce Clostridium difficile Infection in Hospitalized Patients: A Real-world Experience

We assessed the effectiveness of a Lactobacillus probiotic on rates of health care facility–onset Clostridium difficile infection (HO-CDI) in patients receiving antibiotics. A total of 1576 patients were evaluated. There was no difference in the HO-CDI incidence between those who received probiotics...

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Detalles Bibliográficos
Autores principales: Box, Maggie J, Ortwine, Kristine N, Goicoechea, Miguel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2018
Materias:
Brief Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6291414/
https://www.ncbi.nlm.nih.gov/pubmed/30568976
http://dx.doi.org/10.1093/ofid/ofy192
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author Box, Maggie J
Ortwine, Kristine N
Goicoechea, Miguel
author_facet Box, Maggie J
Ortwine, Kristine N
Goicoechea, Miguel
author_sort Box, Maggie J
collection PubMed
description We assessed the effectiveness of a Lactobacillus probiotic on rates of health care facility–onset Clostridium difficile infection (HO-CDI) in patients receiving antibiotics. A total of 1576 patients were evaluated. There was no difference in the HO-CDI incidence between those who received probiotics and those who did not (1.8% vs 0.9%; P = .16).
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spelling pubmed-62914142018-12-19 No Impact of Probiotics to Reduce Clostridium difficile Infection in Hospitalized Patients: A Real-world Experience Box, Maggie J Ortwine, Kristine N Goicoechea, Miguel Open Forum Infect Dis Brief Report We assessed the effectiveness of a Lactobacillus probiotic on rates of health care facility–onset Clostridium difficile infection (HO-CDI) in patients receiving antibiotics. A total of 1576 patients were evaluated. There was no difference in the HO-CDI incidence between those who received probiotics and those who did not (1.8% vs 0.9%; P = .16). Oxford University Press 2018-12-13 /pmc/articles/PMC6291414/ /pubmed/30568976 http://dx.doi.org/10.1093/ofid/ofy192 Text en © The Author(s) 2018. Published by Oxford University Press on behalf of Infectious Diseases Society of America. http://creativecommons.org/licenses/by/4.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Brief Report
Box, Maggie J
Ortwine, Kristine N
Goicoechea, Miguel
No Impact of Probiotics to Reduce Clostridium difficile Infection in Hospitalized Patients: A Real-world Experience
title No Impact of Probiotics to Reduce Clostridium difficile Infection in Hospitalized Patients: A Real-world Experience
title_full No Impact of Probiotics to Reduce Clostridium difficile Infection in Hospitalized Patients: A Real-world Experience
title_fullStr No Impact of Probiotics to Reduce Clostridium difficile Infection in Hospitalized Patients: A Real-world Experience
title_full_unstemmed No Impact of Probiotics to Reduce Clostridium difficile Infection in Hospitalized Patients: A Real-world Experience
title_short No Impact of Probiotics to Reduce Clostridium difficile Infection in Hospitalized Patients: A Real-world Experience
title_sort no impact of probiotics to reduce clostridium difficile infection in hospitalized patients: a real-world experience
topic Brief Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6291414/
https://www.ncbi.nlm.nih.gov/pubmed/30568976
http://dx.doi.org/10.1093/ofid/ofy192
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