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Propofol Inhibits Cerebellar Parallel Fiber-Purkinje Cell Synaptic Transmission via Activation of Presynaptic GABA(B) Receptors in vitro in Mice
Propofol is a widely used intravenous sedative-hypnotic agent, which causes rapid and reliable loss of consciousness via activation of γ -aminobutyric acid A (GABA(A)) receptors. We previously found that propofol inhibited cerebellar Purkinje cells (PC) activity via both GABA(A) and glycine receptor...
Autores principales: | Xuan, Fang-Ling, Wang, Hong-Wei, Cao, Li-Xin, Bing, Yan-Hua, Chu, Chun-Ping, Jin, Ri, Qiu, De-Lai |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6291502/ https://www.ncbi.nlm.nih.gov/pubmed/30574067 http://dx.doi.org/10.3389/fnins.2018.00922 |
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