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Development of Neutralizing and Non-neutralizing Antibodies Targeting Known and Novel Epitopes of TcdB of Clostridioides difficile

Clostridioides difficile is the causative bacterium in 15–20% of all antibiotic associated diarrheas. The symptoms associated with C. difficile infection (CDI) are primarily induced by the two large exotoxins TcdA and TcdB. Both toxins enter target cells by receptor-mediated endocytosis. Although di...

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Detalles Bibliográficos
Autores principales:	Fühner, Viola, Heine, Philip Alexander, Helmsing, Saskia, Goy, Sebastian, Heidepriem, Jasmin, Loeffler, Felix F., Dübel, Stefan, Gerhard, Ralf, Hust, Michael
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2018
Materias:	Microbiology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6291526/ https://www.ncbi.nlm.nih.gov/pubmed/30574127 http://dx.doi.org/10.3389/fmicb.2018.02908

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