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Human Mesenchymal Stem Cell Therapy Reverses Su5416/Hypoxia-Induced Pulmonary Arterial Hypertension in Mice

Aims: Pulmonary arterial hypertension (PAH) is a disease characterized by an increase in pulmonary vascular resistance and right ventricular (RV) failure. We aimed to determine the effects of human mesenchymal stem cell (hMSC) therapy in a SU5416/hypoxia (SuH) mice model of PAH. Methods and Results:...

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Detalles Bibliográficos
Autores principales: Alencar, Allan K. N., Pimentel-Coelho, Pedro M., Montes, Guilherme C., da Silva, Marina de M. C., Mendes, Luiza V. P., Montagnoli, Tadeu L., Silva, Ananssa M. S., Vasques, Juliana Ferreira, Rosado-de-Castro, Paulo Henrique, Gutfilen, Bianca, Cunha, Valéria do M. N., Fraga, Aline G. M., Silva, Patrícia M R e, Martins, Marco Aurélio, Ferreira, Tatiana Paula Teixeira, Mendes-Otero, Rosalia, Trachez, Margarete M., Sudo, Roberto T., Zapata-Sudo, Gisele
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6291748/
https://www.ncbi.nlm.nih.gov/pubmed/30574088
http://dx.doi.org/10.3389/fphar.2018.01395