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Histopathological and patient-related characteristics of basal cell carcinomas of the head and neck influencing therapeutic management
The authors hypothesize that histopathological characteristics of basal cell carcinomas of the head and neck (BCCHN) have changed over time and the correlation of BCCHN localization and histological tumour type can help improving the number and quality of necessary therapeutic interventions. Informa...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
PAGEPress Publications, Pavia, Italy
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6291759/ https://www.ncbi.nlm.nih.gov/pubmed/30603060 http://dx.doi.org/10.4081/dr.2018.7674 |
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author | Holtmann, Henrik Fuhrmann, Vera Sander, Karoline Sproll, Christoph Kübler, Norbert R. Singh, Daman Deep Lommen, Julian |
author_facet | Holtmann, Henrik Fuhrmann, Vera Sander, Karoline Sproll, Christoph Kübler, Norbert R. Singh, Daman Deep Lommen, Julian |
author_sort | Holtmann, Henrik |
collection | PubMed |
description | The authors hypothesize that histopathological characteristics of basal cell carcinomas of the head and neck (BCCHN) have changed over time and the correlation of BCCHN localization and histological tumour type can help improving the number and quality of necessary therapeutic interventions. Information of 222 patients with 344 BCCHN was gained. Descriptive measures were compared to prior studies to prove whether or not characteristics of basal cell carcinomas or patients have changed over time. Afterwards descriptive measures were correlated with number of conducted operations to evaluate if tumour localization, histological tumour type and number of operations depend on one another. Aggravating factors which lead to a higher number of operations were older age, greater size of BCCHN, adjacent elastosis, the localizations eye, ear and nose and histological tumour types morpheaform and nodularulcerated. In comparison to earlier studies characteristics of BCCHN and patients showed positive developments because of grown awareness of BCCHN. Furthermore, our correlations demonstrate that therapeutic results of BCCHN treatment are continuously improving. Nevertheless, treatment of aggressive morpheaform BCCHN in combination with distinctive patient characteristics still needs improvement. |
format | Online Article Text |
id | pubmed-6291759 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2018 |
publisher | PAGEPress Publications, Pavia, Italy |
record_format | MEDLINE/PubMed |
spelling | pubmed-62917592019-01-02 Histopathological and patient-related characteristics of basal cell carcinomas of the head and neck influencing therapeutic management Holtmann, Henrik Fuhrmann, Vera Sander, Karoline Sproll, Christoph Kübler, Norbert R. Singh, Daman Deep Lommen, Julian Dermatol Reports Article The authors hypothesize that histopathological characteristics of basal cell carcinomas of the head and neck (BCCHN) have changed over time and the correlation of BCCHN localization and histological tumour type can help improving the number and quality of necessary therapeutic interventions. Information of 222 patients with 344 BCCHN was gained. Descriptive measures were compared to prior studies to prove whether or not characteristics of basal cell carcinomas or patients have changed over time. Afterwards descriptive measures were correlated with number of conducted operations to evaluate if tumour localization, histological tumour type and number of operations depend on one another. Aggravating factors which lead to a higher number of operations were older age, greater size of BCCHN, adjacent elastosis, the localizations eye, ear and nose and histological tumour types morpheaform and nodularulcerated. In comparison to earlier studies characteristics of BCCHN and patients showed positive developments because of grown awareness of BCCHN. Furthermore, our correlations demonstrate that therapeutic results of BCCHN treatment are continuously improving. Nevertheless, treatment of aggressive morpheaform BCCHN in combination with distinctive patient characteristics still needs improvement. PAGEPress Publications, Pavia, Italy 2018-12-04 /pmc/articles/PMC6291759/ /pubmed/30603060 http://dx.doi.org/10.4081/dr.2018.7674 Text en ©Copyright H. Holtmann et al., 2018 http://creativecommons.org/licenses/by-nc/4.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Article Holtmann, Henrik Fuhrmann, Vera Sander, Karoline Sproll, Christoph Kübler, Norbert R. Singh, Daman Deep Lommen, Julian Histopathological and patient-related characteristics of basal cell carcinomas of the head and neck influencing therapeutic management |
title | Histopathological and patient-related characteristics of basal cell carcinomas of the head and neck influencing therapeutic management |
title_full | Histopathological and patient-related characteristics of basal cell carcinomas of the head and neck influencing therapeutic management |
title_fullStr | Histopathological and patient-related characteristics of basal cell carcinomas of the head and neck influencing therapeutic management |
title_full_unstemmed | Histopathological and patient-related characteristics of basal cell carcinomas of the head and neck influencing therapeutic management |
title_short | Histopathological and patient-related characteristics of basal cell carcinomas of the head and neck influencing therapeutic management |
title_sort | histopathological and patient-related characteristics of basal cell carcinomas of the head and neck influencing therapeutic management |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6291759/ https://www.ncbi.nlm.nih.gov/pubmed/30603060 http://dx.doi.org/10.4081/dr.2018.7674 |
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