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Histopathological and patient-related characteristics of basal cell carcinomas of the head and neck influencing therapeutic management

The authors hypothesize that histopathological characteristics of basal cell carcinomas of the head and neck (BCCHN) have changed over time and the correlation of BCCHN localization and histological tumour type can help improving the number and quality of necessary therapeutic interventions. Informa...

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Autores principales: Holtmann, Henrik, Fuhrmann, Vera, Sander, Karoline, Sproll, Christoph, Kübler, Norbert R., Singh, Daman Deep, Lommen, Julian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: PAGEPress Publications, Pavia, Italy 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6291759/
https://www.ncbi.nlm.nih.gov/pubmed/30603060
http://dx.doi.org/10.4081/dr.2018.7674
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author Holtmann, Henrik
Fuhrmann, Vera
Sander, Karoline
Sproll, Christoph
Kübler, Norbert R.
Singh, Daman Deep
Lommen, Julian
author_facet Holtmann, Henrik
Fuhrmann, Vera
Sander, Karoline
Sproll, Christoph
Kübler, Norbert R.
Singh, Daman Deep
Lommen, Julian
author_sort Holtmann, Henrik
collection PubMed
description The authors hypothesize that histopathological characteristics of basal cell carcinomas of the head and neck (BCCHN) have changed over time and the correlation of BCCHN localization and histological tumour type can help improving the number and quality of necessary therapeutic interventions. Information of 222 patients with 344 BCCHN was gained. Descriptive measures were compared to prior studies to prove whether or not characteristics of basal cell carcinomas or patients have changed over time. Afterwards descriptive measures were correlated with number of conducted operations to evaluate if tumour localization, histological tumour type and number of operations depend on one another. Aggravating factors which lead to a higher number of operations were older age, greater size of BCCHN, adjacent elastosis, the localizations eye, ear and nose and histological tumour types morpheaform and nodularulcerated. In comparison to earlier studies characteristics of BCCHN and patients showed positive developments because of grown awareness of BCCHN. Furthermore, our correlations demonstrate that therapeutic results of BCCHN treatment are continuously improving. Nevertheless, treatment of aggressive morpheaform BCCHN in combination with distinctive patient characteristics still needs improvement.
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spelling pubmed-62917592019-01-02 Histopathological and patient-related characteristics of basal cell carcinomas of the head and neck influencing therapeutic management Holtmann, Henrik Fuhrmann, Vera Sander, Karoline Sproll, Christoph Kübler, Norbert R. Singh, Daman Deep Lommen, Julian Dermatol Reports Article The authors hypothesize that histopathological characteristics of basal cell carcinomas of the head and neck (BCCHN) have changed over time and the correlation of BCCHN localization and histological tumour type can help improving the number and quality of necessary therapeutic interventions. Information of 222 patients with 344 BCCHN was gained. Descriptive measures were compared to prior studies to prove whether or not characteristics of basal cell carcinomas or patients have changed over time. Afterwards descriptive measures were correlated with number of conducted operations to evaluate if tumour localization, histological tumour type and number of operations depend on one another. Aggravating factors which lead to a higher number of operations were older age, greater size of BCCHN, adjacent elastosis, the localizations eye, ear and nose and histological tumour types morpheaform and nodularulcerated. In comparison to earlier studies characteristics of BCCHN and patients showed positive developments because of grown awareness of BCCHN. Furthermore, our correlations demonstrate that therapeutic results of BCCHN treatment are continuously improving. Nevertheless, treatment of aggressive morpheaform BCCHN in combination with distinctive patient characteristics still needs improvement. PAGEPress Publications, Pavia, Italy 2018-12-04 /pmc/articles/PMC6291759/ /pubmed/30603060 http://dx.doi.org/10.4081/dr.2018.7674 Text en ©Copyright H. Holtmann et al., 2018 http://creativecommons.org/licenses/by-nc/4.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Article
Holtmann, Henrik
Fuhrmann, Vera
Sander, Karoline
Sproll, Christoph
Kübler, Norbert R.
Singh, Daman Deep
Lommen, Julian
Histopathological and patient-related characteristics of basal cell carcinomas of the head and neck influencing therapeutic management
title Histopathological and patient-related characteristics of basal cell carcinomas of the head and neck influencing therapeutic management
title_full Histopathological and patient-related characteristics of basal cell carcinomas of the head and neck influencing therapeutic management
title_fullStr Histopathological and patient-related characteristics of basal cell carcinomas of the head and neck influencing therapeutic management
title_full_unstemmed Histopathological and patient-related characteristics of basal cell carcinomas of the head and neck influencing therapeutic management
title_short Histopathological and patient-related characteristics of basal cell carcinomas of the head and neck influencing therapeutic management
title_sort histopathological and patient-related characteristics of basal cell carcinomas of the head and neck influencing therapeutic management
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6291759/
https://www.ncbi.nlm.nih.gov/pubmed/30603060
http://dx.doi.org/10.4081/dr.2018.7674
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