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Salt induction and activation of MtlD, the key enzyme in the synthesis of the compatible solute mannitol in Acinetobacter baumannii

Mannitol is the major compatible solute, next to glutamate, synthesized by the opportunistic human pathogen Acinetobacter baumannii under low water activities. The key enzyme for mannitol biosynthesis, MtlD, was identified. MtlD is highly similar to the bifunctional mannitol‐1‐phosphate dehydrogenas...

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Detalles Bibliográficos
Autores principales: Zeidler, Sabine, Hubloher, Josephine, König, Patricia, Ngu, Ngoc Dinh, Scholz, Anica, Averhoff, Beate, Müller, Volker
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6291793/
https://www.ncbi.nlm.nih.gov/pubmed/29575790
http://dx.doi.org/10.1002/mbo3.614