Cargando…

Reduction of inflammation and T cell activation after 6 months of cART initiation during acute, but not in early chronic HIV-1 infection

OBJECTIVES: To investigate the impact of early combined antiretroviral therapy (cART) on inflammation biomarkers and immune activation during acute and early chronic HIV-1 infection. METHODS: We included 12 acute (AHI), 11 early chronic (EcHI), and 18 late chronic HIV-1-infected (LcHI) individuals w...

Descripción completa

Detalles Bibliográficos
Autores principales:	de Paula, Hury Hellen Souza, Ferreira, Ana Cristina Garcia, Caetano, Diogo Gama, Delatorre, Edson, Teixeira, Sylvia Lopes Maia, Coelho, Lara Esteves, João, Eduarda Grinsztejn, de Andrade, Michelle Morata, Cardoso, Sandra Wagner, Grinsztejn, Beatriz, Veloso, Valdilea Gonçalves, Morgado, Mariza Gonçalves, Guimarães, Monick Lindenmeyer, Côrtes, Fernanda Heloise
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2018
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6291985/ https://www.ncbi.nlm.nih.gov/pubmed/30541557 http://dx.doi.org/10.1186/s12977-018-0458-6

Ejemplares similares

Reduction of HIV-1 Reservoir Size and Diversity After 1 Year of cART Among Brazilian Individuals Starting Treatment During Early Stages of Acute Infection
por: Leite, Thaysse Ferreira, et al.
Publicado: (2019)

Next-generation sequencing analyses of the emergence and maintenance of mutations in CTL epitopes in HIV controllers with differential viremia control
por: Caetano, Diogo Gama, et al.
Publicado: (2018)

A case report of HIV-1 superinfection in an HIV controller leading to loss of viremia control: a retrospective of 10 years of follow-up
por: Caetano, Diogo Gama, et al.
Publicado: (2019)

Increased biomarkers of cardiovascular risk in HIV-1 viremic controllers and low persistent inflammation in elite controllers and art-suppressed individuals
por: Caetano, Diogo Gama, et al.
Publicado: (2022)

HIV-1 elite controllers present a high frequency of activated regulatory T and Th17 cells
por: Caetano, Diogo G., et al.
Publicado: (2020)

Plasmatic Levels of IL-18, IP-10, and Activated CD8(+) T Cells Are Potential Biomarkers to Identify HIV-1 Elite Controllers With a True Functional Cure Profile
por: Côrtes, Fernanda H., et al.
Publicado: (2018)

Association of Single Nucleotide Polymorphisms in the Lens Epithelium-Derived Growth Factor (LEDGF/p75) with HIV-1 Infection Outcomes in Brazilian HIV-1+ Individuals
por: Passaes, Caroline Pereira Bittencourt, et al.
Publicado: (2014)

Cross-Neutralizing Antibodies in HIV-1 Individuals Infected by Subtypes B, F1, C or the B/Bbr Variant in Relation to the Genetics and Biochemical Characteristics of the env Gene
por: de Almeida, Dalziza Victalina, et al.
Publicado: (2016)

Transmitted drug resistance in patients with acute/recent HIV infection in Brazil
por: Ferreira, Ana Cristina G., et al.
Publicado: (2017)

Proviral Quasispecies Diversity Is Not Associated With Virologic Breakthrough or CD4(+) T Cell Loss in HIV-1 Elite Controllers
por: de Azevedo, Suwellen S. D., et al.
Publicado: (2019)

Highly divergent patterns of genetic diversity and evolution in proviral quasispecies from HIV controllers
por: de Azevedo, Suwellen S. D., et al.
Publicado: (2017)

Potential overestimation of HIV-1 sub-subtype F1 circulation in Rio de Janeiro, Brazil
por: Marques, Bianca Cristina Leires, et al.
Publicado: (2018)

Trends in overall opportunistic illnesses, Pneumocystis carinii pneumonia, cerebral toxoplasmosis and Mycobacterium avium complex incidence rates over the 30 years of the HIV epidemic: a systematic review
por: Coelho, Lara, et al.
Publicado: (2013)

Assessing the HIV-1 Epidemic in Brazilian Drug Users: A Molecular Epidemiology Approach
por: Guimarães, Monick Lindenmeyer, et al.
Publicado: (2015)

Ongoing HIV-1 evolution and reservoir reseeding in two elite controllers with genetically diverse peripheral proviral quasispecies
por: de Azevedo, Suwellen Sardinha Dias, et al.
Publicado: (2023)

HIV-1 Diversity and Drug Resistance in Treatment-Naïve Children and Adolescents from Rio de Janeiro, Brazil
por: de Azevedo, Suwellen Sardinha Dias, et al.
Publicado: (2022)

Prevalence, estimated HIV-1 incidence and viral diversity among people seeking voluntary counseling and testing services in Rio de Janeiro, Brazil
por: de Castro, Carlos A Velasco, et al.
Publicado: (2010)

Increased expression of CDKN1A/p21 in HIV-1 controllers is correlated with upregulation of ZC3H12A/MCPIP1
por: de Azevedo, Suwellen S. D., et al.
Publicado: (2020)

Origin and Population Dynamics of a Novel HIV-1 Subtype G Clade Circulating in Cape Verde and Portugal
por: de Pina-Araujo, Isabel Inês M., et al.
Publicado: (2015)

HIV-1 Diversity and Drug Resistance Mutations among People Seeking HIV Diagnosis in Voluntary Counseling and Testing Sites in Rio de Janeiro, Brazil
por: Velasco-de-Castro, Carlos A., et al.
Publicado: (2014)

Comparative HIV-1 Proviral Dynamics in Two Individuals That Maintained Viral Replication Control with or without Antiretroviral Therapy following Superinfection
por: de Azevedo, Suwellen Sardinha Dias, et al.
Publicado: (2022)

Identification of a new circulating recombinant form of human immunodeficiency virus type 1, CRF124_cpx involving subtypes A, G, H, and CRF27_cpx in Angola
por: Da Silva, Rayana Katylin Mendes, et al.
Publicado: (2022)

Genetic Characterization of a New HIV-1 Sub-Subtype A in Cabo Verde, Denominated A8
por: Mendes Da Silva, Rayana Katylin, et al.
Publicado: (2021)

Towards an ideal antiretroviral regimen for the global HIV epidemic
por: Grinsztejn, Beatriz, et al.
Publicado: (2017)

Mortality in patients with HIV-1 and tuberculosis co-infection in Rio de Janeiro, Brazil - associated factors and causes of death
por: da Silva Escada, Rodrigo Otavio, et al.
Publicado: (2017)

Pre-exposure prophylaxis for men and transgender women who have sex with men in Brazil: opportunities and challenges
por: Veloso, Valdilea G, et al.
Publicado: (2015)

Severe infection increases cardiovascular risk among HIV-infected individuals
por: Mesquita, Emersom Cicilini, et al.
Publicado: (2019)

The HIV epidemic in Latin America: accomplishments and challenges on treatment and prevention
por: Luz, Paula M., et al.
Publicado: (2019)

Factors Associated with Tobacco Smoking and Cessation among HIV-Infected Individuals under Care in Rio de Janeiro, Brazil
por: Torres, Thiago S., et al.
Publicado: (2014)

Effectiveness of implementing a decentralized delivery of hepatitis C virus treatment with direct-acting antivirals: A systematic review with meta-analysis
por: Castro, Rodolfo, et al.
Publicado: (2020)

Hospitalization rates, length of stay and in-hospital mortality in a cohort of HIV infected patients from Rio de Janeiro, Brazil
por: Coelho, Lara E., et al.
Publicado: (2016)

Trends in AIDS-Defining Opportunistic Illnesses Incidence over 25 Years in Rio de Janeiro, Brazil
por: Coelho, Lara, et al.
Publicado: (2014)

Aging with HIV: a practical review
por: Cardoso, Sandra Wagner, et al.
Publicado: (2013)

Factors That Could Impact on Liver Fibrosis Staging by Transient Elastography
por: Perazzo, Hugo, et al.
Publicado: (2015)

Chronic Hepatitis C: An Overview of Evidence on Epidemiology and Management from a Brazilian Perspective
por: Castro, Rodolfo, et al.
Publicado: (2015)

Late initiation of antiretroviral therapy: inequalities by educational level despite universal access to care and treatment
por: Rodrigues, Amanda, et al.
Publicado: (2021)

Correction to: Late initiation of antiretroviral therapy: inequalities by educational level despite universal access to care and treatment
por: Rodrigues, Amanda, et al.
Publicado: (2021)

Evaluation of Anti-PF4 Positivity and Platelet Activation after COVID-19 Vaccination with Ad26.COV2.S in Brazil
por: Bokel, Joanna, et al.
Publicado: (2022)

Aging with HIV: an overview of an urban cohort in Rio de Janeiro (Brazil) across decades of life
por: Torres, Thiago Silva, et al.
Publicado: (2013)

Inflammasome genes polymorphisms are associated with progression to mechanical ventilation and death in a cohort of hospitalized COVID-19 patients in a reference hospital in Rio de Janeiro, Brazil
por: Neira-Goulart, Milena, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_2rdvan1ftisk5b3jo64mc0jgq6