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“Omics” data integration and functional analyses link Enoyl-CoA hydratase, short chain 1 to drug refractory dilated cardiomyopathy

BACKGROUND: Large-scale “omics” datasets have not been leveraged and integrated with functional analyses to discover potential drivers of cardiomyopathy. This study addresses the knowledge gap. METHODS: We coupled RNA sequence (RNA-Seq) variant detection and transcriptome profiling with pathway anal...

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Detalles Bibliográficos
Autores principales:	Campbell, Nzali V., Weitzenkamp, David A., Campbell, Ian L., Schmidt, Ronald F., Hicks, Chindo, Morgan, Michael J., Irwin, David C., Tentler, John J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2018
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6292014/ https://www.ncbi.nlm.nih.gov/pubmed/30541556 http://dx.doi.org/10.1186/s12920-018-0439-6

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