Baicalin promotes apoptosis and inhibits proliferation and migration of hypoxia-induced pulmonary artery smooth muscle cells by up-regulating A2a receptor via the SDF-1/CXCR4 signaling pathway

BACKGROUND: Baicalin is a flavonoid compound that exerts specific pharmacological effect in attenuating the proliferation, migration, and apoptotic resistance of hypoxia-induced pulmonary artery smooth muscle cells (PASMCs). However, the underlying mechanism has not been fully elucidated yet. Althou...

Descripción completa

Detalles Bibliográficos
Autores principales: Huang, Xiaoying, Mao, Wei, Zhang, Ting, Wang, Meibin, Wang, Xuetao, Li, Yaozhe, Zhang, Lin, Yao, Dan, Cai, Xueding, Wang, Liangxing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6292092/
https://www.ncbi.nlm.nih.gov/pubmed/30541517
http://dx.doi.org/10.1186/s12906-018-2364-9

Ejemplares similares

Ejemplares similares