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Isoalantolactone induces apoptosis through ROS-mediated ER stress and inhibition of STAT3 in prostate cancer cells

BACKGROUND: Prostate cancer is one of the most commonly diagnosed cancers in men worldwide. Currently available therapies for metastatic prostate cancer are only marginally effective. Therefore, new therapeutic agents are urgently needed to improve patient outcome. Isoalantolactone (IATL), an active...

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Detalles Bibliográficos
Autores principales:	Chen, Wei, Li, Ping, Liu, Yi, Yang, Yu, Ye, Xueting, Zhang, Fangyi, Huang, Hang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2018
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6292114/ https://www.ncbi.nlm.nih.gov/pubmed/30541589 http://dx.doi.org/10.1186/s13046-018-0987-9

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