Identification of TCERG1 as a new genetic modulator of TDP-43 production in Drosophila

TAR DNA-binding protein-43 (TDP-43) is a ubiquitously expressed DNA-/RNA-binding protein that has been linked to numerous aspects of the mRNA life cycle. Similar to many RNA-binding proteins, TDP-43 expression is tightly regulated through an autoregulatory negative feedback loop. Cell function and s...

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Detalles Bibliográficos
Autores principales: Pons, Marine, Prieto, Silvia, Miguel, Laetitia, Frebourg, Thierry, Campion, Dominique, Suñé, Carles, Lecourtois, Magalie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6292132/
https://www.ncbi.nlm.nih.gov/pubmed/30541625
http://dx.doi.org/10.1186/s40478-018-0639-5

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