Cargando…

Randomized comparative trial of diode laser transscleral cyclophotocoagulation versus Ahmed glaucoma valve for neovascular glaucoma in Chinese – a pilot study

PURPOSE: This is a pilot study to compare the effectiveness and safety of diode laser transscleral cyclophotocoagulation (TSCP) with the Ahmed glaucoma valve (AGV) in the management of neovascular glaucoma (NVG). METHODS: Eyes with NVG and an IOP greater than 21 mmHg on maximal medications, without...

Descripción completa

Detalles Bibliográficos
Autores principales: Choy, Bonnie Nga Kwan, Lai, Jimmy Shiu Ming, Yeung, Jane Chun Chun, Chan, Jonathan Cheuk Hung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6292240/
https://www.ncbi.nlm.nih.gov/pubmed/30573944
http://dx.doi.org/10.2147/OPTH.S188999
_version_ 1783380375883481088
author Choy, Bonnie Nga Kwan
Lai, Jimmy Shiu Ming
Yeung, Jane Chun Chun
Chan, Jonathan Cheuk Hung
author_facet Choy, Bonnie Nga Kwan
Lai, Jimmy Shiu Ming
Yeung, Jane Chun Chun
Chan, Jonathan Cheuk Hung
author_sort Choy, Bonnie Nga Kwan
collection PubMed
description PURPOSE: This is a pilot study to compare the effectiveness and safety of diode laser transscleral cyclophotocoagulation (TSCP) with the Ahmed glaucoma valve (AGV) in the management of neovascular glaucoma (NVG). METHODS: Eyes with NVG and an IOP greater than 21 mmHg on maximal medications, without previous glaucoma surgery or cyclodestruction, were randomized for either TSCP or AGV implantation. These eyes were followed for at least 6 months and analyzed with respect to their visual outcome, IOP, number of glaucoma medications required, and related complications. RESULTS: Twenty eyes (eight TSCP and 12 AGV) of 19 subjects with a follow-up duration of greater than 6 months were recruited. Mean follow-up duration was 28.5±17.9 and 31.0±15.4 months for the TSCP and AGV groups, respectively (P=0.80). IOP was successfully controlled in 86% of the eyes for both interventions. By including preservation or improvement of visual acuity as additional criteria for overall success, success decreased to 63% for TSCP and 42% for AGV, although the difference was not statistically significant (P=0.65). Eyes that had TSCP had fewer complications and required less subsequent procedures, compared to those that underwent AGV implantation. CONCLUSION: Both procedures were equally effective in controlling the IOP and reducing glaucoma medications in NVG. However, eyes with AGV implant tended to have higher rates of visual loss and complications, as well as requiring more postoperative procedures, than eyes that were treated with TSCP, although the difference was not statistically significant.
format Online
Article
Text
id pubmed-6292240
institution National Center for Biotechnology Information
language English
publishDate 2018
publisher Dove Medical Press
record_format MEDLINE/PubMed
spelling pubmed-62922402018-12-20 Randomized comparative trial of diode laser transscleral cyclophotocoagulation versus Ahmed glaucoma valve for neovascular glaucoma in Chinese – a pilot study Choy, Bonnie Nga Kwan Lai, Jimmy Shiu Ming Yeung, Jane Chun Chun Chan, Jonathan Cheuk Hung Clin Ophthalmol Original Research PURPOSE: This is a pilot study to compare the effectiveness and safety of diode laser transscleral cyclophotocoagulation (TSCP) with the Ahmed glaucoma valve (AGV) in the management of neovascular glaucoma (NVG). METHODS: Eyes with NVG and an IOP greater than 21 mmHg on maximal medications, without previous glaucoma surgery or cyclodestruction, were randomized for either TSCP or AGV implantation. These eyes were followed for at least 6 months and analyzed with respect to their visual outcome, IOP, number of glaucoma medications required, and related complications. RESULTS: Twenty eyes (eight TSCP and 12 AGV) of 19 subjects with a follow-up duration of greater than 6 months were recruited. Mean follow-up duration was 28.5±17.9 and 31.0±15.4 months for the TSCP and AGV groups, respectively (P=0.80). IOP was successfully controlled in 86% of the eyes for both interventions. By including preservation or improvement of visual acuity as additional criteria for overall success, success decreased to 63% for TSCP and 42% for AGV, although the difference was not statistically significant (P=0.65). Eyes that had TSCP had fewer complications and required less subsequent procedures, compared to those that underwent AGV implantation. CONCLUSION: Both procedures were equally effective in controlling the IOP and reducing glaucoma medications in NVG. However, eyes with AGV implant tended to have higher rates of visual loss and complications, as well as requiring more postoperative procedures, than eyes that were treated with TSCP, although the difference was not statistically significant. Dove Medical Press 2018-12-07 /pmc/articles/PMC6292240/ /pubmed/30573944 http://dx.doi.org/10.2147/OPTH.S188999 Text en © 2018 Choy et al. This work is published and licensed by Dove Medical Press Limited The full terms of this license are available at https://www.dovepress.com/terms.php and incorporate the Creative Commons Attribution – Non Commercial (unported, v3.0) License (http://creativecommons.org/licenses/by-nc/3.0/). By accessing the work you hereby accept the Terms. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed.
spellingShingle Original Research
Choy, Bonnie Nga Kwan
Lai, Jimmy Shiu Ming
Yeung, Jane Chun Chun
Chan, Jonathan Cheuk Hung
Randomized comparative trial of diode laser transscleral cyclophotocoagulation versus Ahmed glaucoma valve for neovascular glaucoma in Chinese – a pilot study
title Randomized comparative trial of diode laser transscleral cyclophotocoagulation versus Ahmed glaucoma valve for neovascular glaucoma in Chinese – a pilot study
title_full Randomized comparative trial of diode laser transscleral cyclophotocoagulation versus Ahmed glaucoma valve for neovascular glaucoma in Chinese – a pilot study
title_fullStr Randomized comparative trial of diode laser transscleral cyclophotocoagulation versus Ahmed glaucoma valve for neovascular glaucoma in Chinese – a pilot study
title_full_unstemmed Randomized comparative trial of diode laser transscleral cyclophotocoagulation versus Ahmed glaucoma valve for neovascular glaucoma in Chinese – a pilot study
title_short Randomized comparative trial of diode laser transscleral cyclophotocoagulation versus Ahmed glaucoma valve for neovascular glaucoma in Chinese – a pilot study
title_sort randomized comparative trial of diode laser transscleral cyclophotocoagulation versus ahmed glaucoma valve for neovascular glaucoma in chinese – a pilot study
topic Original Research
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6292240/
https://www.ncbi.nlm.nih.gov/pubmed/30573944
http://dx.doi.org/10.2147/OPTH.S188999
work_keys_str_mv AT choybonniengakwan randomizedcomparativetrialofdiodelasertransscleralcyclophotocoagulationversusahmedglaucomavalveforneovascularglaucomainchineseapilotstudy
AT laijimmyshiuming randomizedcomparativetrialofdiodelasertransscleralcyclophotocoagulationversusahmedglaucomavalveforneovascularglaucomainchineseapilotstudy
AT yeungjanechunchun randomizedcomparativetrialofdiodelasertransscleralcyclophotocoagulationversusahmedglaucomavalveforneovascularglaucomainchineseapilotstudy
AT chanjonathancheukhung randomizedcomparativetrialofdiodelasertransscleralcyclophotocoagulationversusahmedglaucomavalveforneovascularglaucomainchineseapilotstudy