mTHPC-loaded extracellular vesicles outperform liposomal and free mTHPC formulations by an increased stability, drug delivery efficiency and cytotoxic effect in tridimensional model of tumors

Efficient photodynamic therapy with meta-tetra(hydroxyphenyl)chlorine requires the application of specific nanoformulations. mTHPC liposomal formulation (Foslip(®)) demonstrated favorable pharmacokinetics properties. However, rapid liposomes destruction in circulation and rapid mTHPC release impedes...

Descripción completa

Detalles Bibliográficos
Autores principales: Millard, Marie, Yakavets, Ilya, Piffoux, Max, Brun, Amanda, Gazeau, Florence, Guigner, Jean-Michel, Jasniewski, Jordane, Lassalle, Henri-Pierre, Wilhelm, Claire, Bezdetnaya, Lina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6292368/
https://www.ncbi.nlm.nih.gov/pubmed/30785308
http://dx.doi.org/10.1080/10717544.2018.1513609

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6292368/
https://www.ncbi.nlm.nih.gov/pubmed/30785308
http://dx.doi.org/10.1080/10717544.2018.1513609

Ejemplares similares