Therapeutic decision based on molecular detection of resistance mechanism in an ALK-rearranged lung cancer patient: a case report

BACKGROUND: The use of tyrosine kinase inhibitors (TKIs) of ALK is the therapy of choice for ALK-fusion patients. Unfortunately, all patients under this kind of treatment eventually develop acquired resistance through several well-known mechanisms, such as acquisition of a secondary mutation within...

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Detalles Bibliográficos
Autores principales: De Carlo, Elisa, Schiappacassi, Monica, Urbani, Martina, Doliana, Roberto, Baldassarre, Gustavo, Da Ros, Valentina, Santarossa, Sandra, Chimienti, Emanuela, Berto, Eleonora, Fratino, Lucia, Bearz, Alessandra
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2018
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6292407/
https://www.ncbi.nlm.nih.gov/pubmed/30573982
http://dx.doi.org/10.2147/OTT.S184745

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