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Specificity and mechanism of carbohydrate demethylation by cytochrome P450 monooxygenases
Degradation of carbohydrates by bacteria represents a key step in energy metabolism that can be inhibited by methylated sugars. Removal of methyl groups, which is critical for further processing, poses a biocatalytic challenge because enzymes need to overcome a high energy barrier. Our structural an...
Autores principales: | Robb, Craig S., Reisky, Lukas, Bornscheuer, Uwe T., Hehemann, Jan-Hendrik |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Portland Press Ltd.
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6292453/ https://www.ncbi.nlm.nih.gov/pubmed/30404923 http://dx.doi.org/10.1042/BCJ20180762 |
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