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Sensitivity to inhibition of DNA repair by Olaparib in novel oropharyngeal cancer cell lines infected with Human Papillomavirus
The incidence of Human Papillomavirus (HPV)-associated oropharyngeal squamous cell carcinoma (OPSCC) is increasing rapidly in the UK. Patients with HPV-positive OPSCC generally show superior clinical responses relative to HPV-negative patients. We hypothesised that these superior responses could be...
Autores principales: | Pirotte, Evelyne F., Holzhauser, Stefan, Owens, David, Quine, Stuart, Al-Hussaini, Ali, Christian, Adam D., Giles, Peter J., Man, Stephen T., Evans, Mererid, Powell, Ned G. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6292594/ https://www.ncbi.nlm.nih.gov/pubmed/30543656 http://dx.doi.org/10.1371/journal.pone.0207934 |
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