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Identification of PSD-95 in the Postsynaptic Density Using MiniSOG and EM Tomography

Combining tomography with electron microscopy (EM) produces images at definition sufficient to visualize individual protein molecules or molecular complexes in intact neurons. When freeze-substituted hippocampal cultures in plastic sections are imaged by EM tomography, detailed structures emerging f...

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Detalles Bibliográficos
Autores principales: Chen, Xiaobing, Winters, Christine, Crocker, Virginia, Lazarou, Michael, Sousa, Alioscka A., Leapman, Richard D., Reese, Thomas S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6292990/
https://www.ncbi.nlm.nih.gov/pubmed/30581381
http://dx.doi.org/10.3389/fnana.2018.00107