Salt stress in the renal tubules is linked to TAL-specific expression of uromodulin and an upregulation of heat shock genes

Previously, our comprehensive cardiovascular characterization study validated Uromodulin as a blood pressure gene. Uromodulin is a glycoprotein exclusively synthesized at the thick ascending limb of the loop of Henle and is encoded by the Umod gene. Umod(−/−) mice have significantly lower blood pres...

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Detalles Bibliográficos
Autores principales: Graham, Lesley A., Aman, Alisha, Campbell, Desmond D., Augley, Julian, Graham, Delyth, McBride, Martin W., Fraser, Niall J., Ferreri, Nicholas R., Dominiczak, Anna F., Padmanabhan, Sandosh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Physiological Society 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6293113/
https://www.ncbi.nlm.nih.gov/pubmed/30216136
http://dx.doi.org/10.1152/physiolgenomics.00057.2018

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6293113/
https://www.ncbi.nlm.nih.gov/pubmed/30216136
http://dx.doi.org/10.1152/physiolgenomics.00057.2018

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