Cargando…

Treatment of diffuse sclerosing osteomyelitis of the jaw with denosumab shows remarkable results—A report of two cases

Denosumab may play a central role in the treatment of diffuse sclerosing osteomyelitis of the mandible. This report describes two patients who had been treated unsuccessfully with antibiotics and steroids for several years. After denosumab treatment, both patients became pain‐free and the radiologic...

Descripción completa

Detalles Bibliográficos
Autores principales: Hallmer, Fredrik, Korduner, Mikael, Møystad, Anne, Bjørnland, Tore
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6293128/
https://www.ncbi.nlm.nih.gov/pubmed/30564344
http://dx.doi.org/10.1002/ccr3.1894
_version_ 1783380492893028352
author Hallmer, Fredrik
Korduner, Mikael
Møystad, Anne
Bjørnland, Tore
author_facet Hallmer, Fredrik
Korduner, Mikael
Møystad, Anne
Bjørnland, Tore
author_sort Hallmer, Fredrik
collection PubMed
description Denosumab may play a central role in the treatment of diffuse sclerosing osteomyelitis of the mandible. This report describes two patients who had been treated unsuccessfully with antibiotics and steroids for several years. After denosumab treatment, both patients became pain‐free and the radiological examination showed less severe osteomyelitis.
format Online
Article
Text
id pubmed-6293128
institution National Center for Biotechnology Information
language English
publishDate 2018
publisher John Wiley and Sons Inc.
record_format MEDLINE/PubMed
spelling pubmed-62931282018-12-18 Treatment of diffuse sclerosing osteomyelitis of the jaw with denosumab shows remarkable results—A report of two cases Hallmer, Fredrik Korduner, Mikael Møystad, Anne Bjørnland, Tore Clin Case Rep Case Reports Denosumab may play a central role in the treatment of diffuse sclerosing osteomyelitis of the mandible. This report describes two patients who had been treated unsuccessfully with antibiotics and steroids for several years. After denosumab treatment, both patients became pain‐free and the radiological examination showed less severe osteomyelitis. John Wiley and Sons Inc. 2018-10-26 /pmc/articles/PMC6293128/ /pubmed/30564344 http://dx.doi.org/10.1002/ccr3.1894 Text en © 2018 The Authors. Clinical Case Reports published by John Wiley & Sons Ltd. This is an open access article under the terms of the http://creativecommons.org/licenses/by/4.0/ License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Reports
Hallmer, Fredrik
Korduner, Mikael
Møystad, Anne
Bjørnland, Tore
Treatment of diffuse sclerosing osteomyelitis of the jaw with denosumab shows remarkable results—A report of two cases
title Treatment of diffuse sclerosing osteomyelitis of the jaw with denosumab shows remarkable results—A report of two cases
title_full Treatment of diffuse sclerosing osteomyelitis of the jaw with denosumab shows remarkable results—A report of two cases
title_fullStr Treatment of diffuse sclerosing osteomyelitis of the jaw with denosumab shows remarkable results—A report of two cases
title_full_unstemmed Treatment of diffuse sclerosing osteomyelitis of the jaw with denosumab shows remarkable results—A report of two cases
title_short Treatment of diffuse sclerosing osteomyelitis of the jaw with denosumab shows remarkable results—A report of two cases
title_sort treatment of diffuse sclerosing osteomyelitis of the jaw with denosumab shows remarkable results—a report of two cases
topic Case Reports
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6293128/
https://www.ncbi.nlm.nih.gov/pubmed/30564344
http://dx.doi.org/10.1002/ccr3.1894
work_keys_str_mv AT hallmerfredrik treatmentofdiffusesclerosingosteomyelitisofthejawwithdenosumabshowsremarkableresultsareportoftwocases
AT kordunermikael treatmentofdiffusesclerosingosteomyelitisofthejawwithdenosumabshowsremarkableresultsareportoftwocases
AT møystadanne treatmentofdiffusesclerosingosteomyelitisofthejawwithdenosumabshowsremarkableresultsareportoftwocases
AT bjørnlandtore treatmentofdiffusesclerosingosteomyelitisofthejawwithdenosumabshowsremarkableresultsareportoftwocases