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MDM2 inhibitor ameliorates cisplatin‐induced nephropathy via NFκΒ signal inhibition

Cisplatin is a platinum‐containing chemotherapeutic drug, which is widely used and highly effective. While effective against tumors, its use is limited by severe side effects such as nephrotoxicity and bone marrow suppression. Murine double minute 2 (MDM2) is the E3 ubiquitin ligase of the tumor sup...

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Detalles Bibliográficos
Autores principales:	Fujikura, Tomoyuki, Yasuda, Hideo, Iwakura, Takamasa, Tsuji, Takayuki, Anders, Hans‐J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2018
Materias:	Original Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6293176/ https://www.ncbi.nlm.nih.gov/pubmed/30564368 http://dx.doi.org/10.1002/prp2.450

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