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Integrating Experiment and Theory to Understand TCR-pMHC Dynamics
The conformational dynamism of proteins is well established. Rather than having a single structure, proteins are more accurately described as a conformational ensemble that exists across a rugged energy landscape, where different conformational sub-states interconvert. The interaction between αβ T c...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Frontiers Media S.A.
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6293202/ https://www.ncbi.nlm.nih.gov/pubmed/30581442 http://dx.doi.org/10.3389/fimmu.2018.02898 |